유치열에서 Chlorhexidine Varnish와 Polyurethane Sealant의 Streptococcus mutans억제 효과에 대한 연구
THE INHIBITORY EFFECT OF CHLORHEXIDINE VARNISH AND POLYURETHANE SEALANT ON SYREPTOCOCCUS MUTANS IN THE PRIMARY DENTITION
이성혁, 장기택, 김종철,
소속 상세정보
이성혁 ( ) - 서울대학교 치과대학 소아치과학교
장기택 ( ) - 서울대학교 치과대학 소아치과학교
김종철 ( ) - 서울대학교 치과대학 소아치과학교
KMID : 0358919980250010116
Abstract
결 론
치아우식증은 아동의 가장 흔한 구강질환이며, 이것의 원인균은 S.mutans로 알려져 있다.
이에 저자는 유치열에서 chlorhexidine varnish와 polyurethane sealant에 의한 S.mutans의
억제 효과를 알아보기 위해 본 실험을 시행하였다.
활동성 우식이 없고 유치열만을 가진 3-5세의 아동을 대상으로 chlorhexidine varnish와
polyurethane sealent를 도포하기 전과 후 타액내의 S.mutans수를 검사하여 다음과 같은 결
론을 얻었다.
1. Ghlorhexidine varnish와 Polyurethane sealant는 구강내 Streptococcus mutans의 수를
5주(P<0.01) 12주(P<0.05)까지는 통계학적으로 유의성있게 억제하였으나 24주에서는 유의성
있는 변화가 나타나지 않았다.
2. Chlorhexidine varnish와 polyurethane sealant도포에 의한 Streptococcus mutans억제
효과는 지속적이지 않으므로 12∼24주 사이 재도포가 필요하다.
#초록#
Numerous chemical agents have 1)eon developed to reduce the activity of cariogenic
bacteria. Of these, chlorhexidine is acknowledged as the most effective. Gel and
mouthrinse have been the traditional method of its application in the mouth. It has been
reported that chlorhexidine varnish has proyurethane inhibitory effect on the number of
streptococcus mutans in saliva and plaque. Recently, chlorhexidine varnish and
polyurethane sealant have been developed to promote prolonged anticariogenic effect of
chlorhexidine. Products containing 10% chlorhexidine varnish and polyurethane sealant
have been developed to prevent cables by reducing the number of Streptococcus mutans
in the oral cavity.
The purpose of this study is to investigate the inhibitory effect of chlorhexidine
varnish and polyurethane sealant on streptococcus mutans in the primary dentition.
Children with primary dentition containing no active carious lesion were divided into
two groups. To the experimental group(n=11), chlorhexidine varnish and polyurethane
sealant (ChlorzoinR, Knowell Therapeutic Technologies, Inc. Canada.) was
applied once a week for four weeks according to the manufacturer's instruction. Only
oral prophylaxis was performed on the control group(n=7). Caries activity was measured
after using CariescreenRSM (Knowell Therapeutic Technologies, Inc.
Canada.) to incubate streptococcus mutans before and 5, 12, 24 weeks after initial
varnish application. The following results were observed.,
1. There was statistically significant decrease in the number of streptococcus mutants
in the experimental group for 5 weeks(P<0.01), 12 weeks(P<0.05) after the initial
application. but, by 24 weeks significant difference had disappeared.
2. As the inhibitory effect of chlorhexidine varnish and polyurethane sealant application
is not everlasting, reapplication at l2-24 weeks should be needed.
키워드
Chlorhexidine varnish; Polyurethane sealant; Streptococcus mutans Deciduous;
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